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Substance	Sorafenib
Brand name:	Nexavar
Description
	Chemotherapy
	Nexavar is an anticancer drug, a protein kinase inhibitor. The active ingredient of Nexavar sorafenib is a multi-kinase inhibitor that inhibits the activity of a number of intracellular kinases
Brands:	Nexavar
Availability:	Prescription needed
Pregnancy:	Consult a doctor
Alcohol:	Not detected with light alcohol consumption
Side Effects:	Dizziness, Depressed Mood, Joint Pain Or Swelling
Interactions:	Levothyroxine, Ondansetron, Fluoxetine
For informational purposes only. Consult your local medical authority for advice.

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What may interact with Nexavar?

Tell your doctor about all other cancer medicines you use, especially cisplatin, cyclophosphamide, docetaxel, doxorubicin, fluorouracil, gemcitabine, irinotecan, paclitaxel, or tamoxifen.

Many drugs can interact with sorafenib. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with sorafenib, especially:

• dexamethasone;

• neomycin;

• St. John's wort;

• a blood thinner (warfarin, Coumadin);

• seizure medication--carbamazepine, fosphenytoin, phenobarbital, phenytoin; or

• tuberculosis medicine--rifabutin, rifampin.

This list is not complete and many other drugs can interact with sorafenib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

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